Déjà Dup is a nice graphical wrapper around the command line backup tool duplicity. It hides the complexity of backing up the Right Way (encrypted, off-site, and regular) and uses duplicity as the back end. Déjà Dup does not use cron or similar schedulers. Rather, it starts a program deja-dup-monitor when you log into your session. This keeps track of when you last successfully backed up and will wait until the next scheduled backup.
Back ups are very important. Probably something I should do with my desktops more often.